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Cyclodextrins in oligonucleotide delivery

✍ Scribed by Enrico Redenti; Claudio Pietra; Andrea Gerloczy; Lajos Szente

Book ID: 114176024
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 83 KB
Volume: 53
Category: Article
ISSN: 0169-409X
DOI: 10.1016/s0169-409x(01)00230-7

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Oligonucleotides (ONs) are a new class of therapeutic compounds under investigation for the treatment of a variety of disease states, such as cancer and HIV, and for FDA approval of an anti-CMV retinitis antisense molecule (Vitravene trade mark, Isis Pharmaceuticals). However, these molecules are li