Cyclobutane analogs of GABA
โ Scribed by R. D. Allan; D. R. Curtis; P. M. Headley; G. A. R. Johnston; S. M. E. Kennedy; D. Lodge; B. Twitchin
- Book ID
- 105017053
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 446 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0364-3190
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๐ SIMILAR VOLUMES
A rigid GABA analog has been prepared from the adduct obtained from the [4+3]-cycloaddition of pentachloroacetone and a 2-substituted furan.
Gabapentin and Pregabalin are both 3-alkylated โฅ-amino butyric acid (GABA) analogs. Gabapentin was designed as a lipophilic GABA analog and was first synthesized as a potential anticonvulsant and was launched in 1994 as add-on therapy for the treatment of epilepsy. In this review the discovery and d
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