Cycloadditions of nitrile oxides and nitrones to 4,4-methylene-1-methylpiperidine: Studies in regio- and stereoselectivity
✍ Scribed by L. Fišera; F. Sauter; J. Fröhlich; Y. Feng; P. Ertl; K. Mereiter
- Publisher
- Springer Vienna
- Year
- 1994
- Tongue
- English
- Weight
- 610 KB
- Volume
- 125
- Category
- Article
- ISSN
- 0026-9247
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Cycloaddition of nitrile oxides to 4-vinyl-2-oxazoline 1 and to 4-vinyloxazolidine 2 afford diastereomeric mixtures of 2-isoxazolines in which the eryrhro product predominates (32-64% d.e.). In contrast, the cortesponding reactions with acyclic analogue 3 favoured the fhreoadducts and were less sele
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In the pre~nce ~ff ~xtium methoxide in catalytic amount, conjugated azoalkenes sm<x~thly add at rtx~m temperature (phenylsulphonyl)acetamide, methyl (phenylsulphonyl)acetate, methyl (phenylsulphinyl)acetate, (arylsulphonyl)acetonitriles, bis(phenylsulphonyl)methane. 'and (arylsulphonyl)nim~methane t