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Cycloadditions of Cephalosporins. A Comprehensive Study of the Reaction of Cephalosporin Triflates with Olefins, Acetylenes, and Dienes To Form [2 + 2] and [4 + 2] Adducts

✍ Scribed by Elliott, Richard L.; Nicholson, Neville H.; Peaker, Fiona E.; Takle, Andrew K.; Richardson, Christine M.; Tyler, John W.; White, Janet; Pearson, Michael J.; Eggleston, Drake S.; Haltiwanger, R. Curtis


Book ID
120044284
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
730 KB
Volume
62
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Cycloadditions of C
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

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Cycloaddition reactions of cephalosporin
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A series of known and novel 2-methylenecephem derivatives were prepared and their reactions with diazomethane, phenyldiazomethane and diphenyldiazomethane were studied. The initially formed 1-pyrazolino derivatives easily underwent spontaneous loss of nitrogen, leading to 2-spirocyclopropylcephems.