The reaction of 0-trimethylsilyl a-bromo aldoximes with unsaturated alcohols produces oximino ethers which can be readily oxidized with sodium hypochlorite. The transient nitrile oxide intermediate formed undergoes spontaneous cyclization affording fused isoxazolines. MM2 calculations help rationali
โฆ LIBER โฆ
Cycloadditions, 47. A Route to Functionalized Cyclic Ethers by Intramolecular Cycloadditions of Unsaturated Nitro Ethers
โ Scribed by Hassner, Alfred ;Dehaen, Wim
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1991
- Tongue
- English
- Weight
- 645 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0009-2940
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