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Cycloadditionen, 18. 5-Aminoisoxazole durch Cycloaddition von Nitriloxiden an Inamine

✍ Scribed by Himbert, Gerhard ;Kuhn, Hildegard ;Barz, Michael


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
485 KB
Volume
1990
Category
Article
ISSN
0947-3440

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✦ Synopsis


Cycloadditions, 18. — 5‐Aminoisoxazoles by Cycloaddition of Nitrile Oxides to Ynamines

Ten differently substituted ynamines 1a–j react with five nitrile oxides 3a–e to give the 5‐aminoisoxazoles 4a–z. The stannyl‐substituted ynamine 1c furnishes the same compounds (e.g. 4a–d) by reaction with the hydroximoyl chlorides 2a–d. Two representatives of 4–b and p ‐ can be transformed into the corresponding 1‐azirine‐3‐carboxamides 6a and b.