The reactions of diazoalkanes with tropone have been reported to produce 2,4,6cyclooctatrienones as the only products.2 However, in the course of our studies of periselectivity in 1,3-dipolar cycloadditions to trienes,"' we have found that cyclooctatrienone is but one of many products formed upon re
Cycloaddition reactions of cephalosporin compounds I. The cycloaddition of diazomethane to the cephem nucleus.
✍ Scribed by E.R. Farkas; E.T. Gunda; J.Cs. Jászberényi
- Publisher
- Elsevier Science
- Year
- 1973
- Tongue
- French
- Weight
- 173 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0040-4039
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A series of known and novel 2-methylenecephem derivatives were prepared and their reactions with diazomethane, phenyldiazomethane and diphenyldiazomethane were studied. The initially formed 1-pyrazolino derivatives easily underwent spontaneous loss of nitrogen, leading to 2-spirocyclopropylcephems.
## Abstract The rate of the thermal cycloaddition of ethylene to __cis__ and __trans__ butene‐2 has been measured at 693°K and at pressures of about 12 atmospheres. The ratio of __trans__‐ to __cis__‐1,2‐dimethylcyclobutane from the reaction of __trans__‐butene‐2 with ethylene was 5.1, obtained fro