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Cycloaddition of Bis-1,3-dipolar Reagents to 1,3-Diarylprop-2-en-1-ones.

✍ Scribed by V. Padmavathi; G. Siva Jyothi; N. Y. Sreedhar; K. Venugopal Reddy; T. V. Ramana Reddy; D. Bhaskar Reddy


Publisher
John Wiley and Sons
Year
2003
Weight
134 KB
Volume
34
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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Stereoselective 1,3-Dipolar Cycloadditio
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Benzoyl-3-[(E)-cyanomethylidene]-5-(methoxycarbonyl)pyrrolidin-2-one (5) was prepared in four steps from l-pyroglutamic acid (1). 1,3-Dipolar cycloadditions of diazomethane ( 6) and 2,4,6-trimethoxybenzonitrile oxide (7) gave substituted 1,2,7-triazaspiro[4.4]non-1-en-6-one 12 and 1-oxa-2,7-diazaspi