Cyclo-oxygenase 2 inhibition in colorectal cancer therapy
โ Scribed by R. D. Church; J. W. Fleshman; H. L. McLeod
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 297 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0007-1323
- DOI
- 10.1002/bjs.4297
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Regular administration of non-steroidal anti-inflammatory drugs (NSAIDs) may reduce the incidence of colorectal cancer by targeting cyclo-oxygenase-2 (Cox-2), a key enzyme in arachidonic acid metabolism. To evaluate the role of Cox-2 in sporadic colorectal cancer development, Cox-2 expression was in
Many colorectal cancers have high levels of cyclo-oxygenase 2 (COX-2), an enzyme that metabolizes the essential fatty acids into prostaglandins. Since the low-density lipoprotein receptor (LDLr) is involved in the uptake of essential fatty acids, we studied the effect of LDL on growth and gene regul