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Cyclization of vinyl radicals: a versatile method for the construction of five- and six-membered rings

✍ Scribed by Stork, G.; Baine, Neil H.


Book ID
115459491
Publisher
American Chemical Society
Year
1982
Tongue
English
Weight
404 KB
Volume
104
Category
Article
ISSN
0002-7863

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Six- versus five-membered ring formation
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Radical cyclization of 1-vinyl-5-methyl-5-hexenyl radicals (radical numbering) affords six-membered ring products prevailing over the isomeric five-membered ring compounds; the former are generated through two reaction pathways: 6-endo-trig ring closure and rearrangement of intermediate methylenecyc