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Cyclization of o-phenylenediamines by CO2in the presence of H2for the synthesis of benzimidazoles

✍ Scribed by Yu, Bo ;Zhang, Hongye ;Zhao, Yanfei ;Chen, Sha ;Xu, Jilei ;Huang, Changliang ;Liu, Zhimin


Book ID
118124223
Publisher
Royal Society of Chemistry
Year
2013
Tongue
English
Weight
258 KB
Volume
15
Category
Article
ISSN
1463-9262

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Cobalt-mediated synthesis of 2-(4-pyridy
✍ Zhiyong Wang; Scott R. Wilson; Bruce M. Foxman; Wenbin Lin πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 239 KB

We have observed an unusual example of cobalt-mediated cyclization of 4-pyridinecarboxaldehyde and 2-nitroaniline to afford 2-(4-pyridyl)benzimidazole under hydro(solvo)thermal conditions. Reaction of Co(NO 3 ) 2 ⅐6H 2 O with 4-pyridinecarboxaldehyde and 2-nitroaniline in ethanol at 120Β°C gave a cob