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Cyclization of 3-Hydroxy-3-alkyl-2-(2-hydroxyethylthio)-1-butenecarbonitriles to 5-aminofuran-3-ones

✍ Scribed by Yu. M. Skvortsov; E. I. Moshchevitina; A. G. Mal'kina


Publisher
Springer US
Year
1988
Tongue
English
Weight
72 KB
Volume
24
Category
Article
ISSN
0009-3122

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Cyclization of 1-alkylamino-3-halo-2-alk
✍ V.R. Gaertner πŸ“‚ Article πŸ“… 1966 πŸ› Elsevier Science 🌐 French βš– 182 KB

We describe here a simple two-step synthesis of l-alkyl-3-azetldlnols, whereby this new series becomes the most readily prepared class of azetidlnes. The method points to a general conversion of complex primary amines to 3-azetldlnols, as well as providing an entree into the 3-substituted azetldines