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Cyclin-dependent kinase inhibitor (CDKI) expression in quiescent and proliferating rat hepatocytes

โœ Scribed by M. Barone; A. Moretti; R. Ladisa; C. Abbatangelo; L. Polimeno; A. Francavilla; A. Iolascon

Book ID
119629772
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
170 KB
Volume
32
Category
Article
ISSN
1590-8658

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The p21 protein is a universal inhibitor of cyclindependent kinases and of cell-cycle progression and is involved in numerous growth-inhibitory pathways in cell culture systems. Recent studies suggest that p21 regulates hepatocyte cell cycle progression in models of liver regeneration. The present s