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Cyclin-Dependent Kinase Inhibition With Roscovitine: Neuroprotection in Acute Ischemic Stroke

✍ Scribed by Timsit, S; Menn, B


Book ID
124168967
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
192 KB
Volume
91
Category
Article
ISSN
0009-9236

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The cyclin-dependent kinase inhibitor ro
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## Abstract Roscovitine, a cyclin‐dependent kinase (Cdk) inhibitor, inhibited kinase activity and the axenic growth of __Dictyostelium discoideum__ at micromolar concentrations. Growth was almost fully rescued in 50 ¡M and ∼50% rescued in 100 ¡M roscovitine‐treated cultures by the over‐expression o