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Cyclin D1 overexpression in thyroid papillary microcarcinoma: its association with tumour size and aberrant β-catenin expression

✍ Scribed by D Lantsov; S Meirmanov; M Nakashima; H Kondo; V Saenko; Y Naruke; H Namba; M Ito; A Abrosimov; E Lushnikov; I Sekine; Sh Yamashita


Book ID
108779974
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
791 KB
Volume
47
Category
Article
ISSN
0309-0167

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␤-Catenin is a component of the E-cadherin-catenin cell adhesion complex. It plays also a role in intracellular signaling and can function as an oncogene when it binds to the T-cell factor 4 (Tcf4)-binding site in the promoter region of cyclin D1 and transactivates genes after translocation to the n