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Cyclical DNA methylation of a transcriptionally active promoter

✍ Scribed by Gallais, Rozenn; Tiffoche, Christophe; Le Péron, Christine; Jurkowska, Renata Z.; Carmouche, Richard P.; Ibberson, David; Barath, Peter; Demay, Florence; Reid, George; Métivier, Raphaël

Book ID
109897212
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
853 KB
Volume
452
Category
Article
ISSN
0028-0836

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## Abstract We have shown that prostasin serine protease is downregulated in high‐grade prostate tumors and inhibits invasiveness of prostate cancer cell lines upon enforced reexpression. In our study, prostasin mRNA and protein were shown to be expressed in normal human mammary epithelial cells (N