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Cyclic Sulfamidates as Lactam Precursors. An Efficient Asymmetric Synthesis of (-)-Aphanorphine.

✍ Scribed by John F. Bower; Peter Szeto; Timothy Gallagher

Publisher
John Wiley and Sons
Year
2006
Weight
26 KB
Volume
37
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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## Abstract Introduction of structural constraint into peptides is an effective way for studying their conformation–activity relationships. Conformationally restrained dipeptidyl lactams, important building blocks for the synthesis of peptidomimetics, have now been synthesized from **N**‐[9‐(9‐phen