Dynamic kinetic resolution of suprofen t
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Chun-Nan Lin; Shau-Wei Tsai
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Article
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2000
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John Wiley and Sons
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English
โ 150 KB
๐ 2 views
A lipase-catalyzed enantioselective hydrolysis process under conditions of continuous in situ racemization of substrate with trioctylamine as the catalyst was developed for the production of (S)-suprofen from (R,S)-suprofen 2,2,2-trifluoroethyl thioester in isooctane. A detailed investigation of tri