Cyclic Nucleotides and Growth Control in Cultured Mouse Cells: Correlation of Changes in Intracellular 3′:5′cGMP Concentration with a Specific Phase of the Cell Cycle

Correlation between growth rate, cell de

Correlation between growth rate, cell density, and intracellular concentrations of cyclic nucleotides in chemsostat cultures of mouse L1210 cells

✍ Michael G. Tovey; Cécile Rochette-Egly; Monique Castagna 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 364 KB

## Abstract Constant intracellular concentration of both adenosine 3′,5′ cyclic monophosphate (cyclic AMP) and guanosine 3′,5′ cyclic monophosphate (cyclic GMP) were obtained when mouse leukemia L1210 cells were cultivated under steady‐state conditions in the chemostat. When L1210 cells were mainta