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Cyclic nucleotide phosphodiesterase inhibition by imidazopyridines: analogs of sulmazole and isomazole as inhibitors of the cGMP specific phosphodiesterase

✍ Scribed by Coates, William J.; Connolly, Brendan; Dhanak, Dashyant; Flynn, Sean T.; Worby, Angela


Book ID
115450558
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
786 KB
Volume
36
Category
Article
ISSN
0022-2623

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Cyclic nucleotide phosphodiesterases and
✍ Ana Castro; Maria Jose Jerez; Carmen Gil; Ana Martinez πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 187 KB

## Abstract The activity of phosphodiesterases (PDEs) is associated with a wide variety of diseases and an intense effort toward the development of specific PDEs inhibitors has been generated for the last years. They are the enzymes responsible for the hydrolysis of intracellular cyclic adenosine a