Effect of purkinje cell loss on cerebell
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Dr. T. N. Seyfried; D. J. Bernard; R. K. Yu
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Article
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1987
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John Wiley and Sons
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English
⚖ 483 KB
The distribution of cerebellar gangliosides was studied in adult (73 +/- 2 days) nervous (nr/nr) mutant mice which lose 50-90% of their Purkinje cells. This neuronal loss is associated with significant reductions in cerebellar weight and ganglioside concentration. The cerebellar dry weights (mg) and