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Cyclic enkephalin and dermorphin analogues containing a carbonyl bridge

✍ Scribed by Katarzyna Filip; Marta Oleszczuk; Jacek Wójcik; Nga N. Chung; Peter W. Schiller; Danuta Pawlak; Agnieszka Zieleniak; Agnieszka Parcińska; Ewa Witkowska; Professor Jan Izdebski


Book ID
105360427
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
149 KB
Volume
11
Category
Article
ISSN
1075-2617

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📜 SIMILAR VOLUMES


Potent side-chain to side-chain cyclized
✍ Katarzyna Filip; Marta Oleszczuk; Danuta Pawlak; Jacek Wójcik; Nga N. Chung; Pet 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB

## Abstract A new family of cyclic opioid peptide analogues related to the 1–4 sequence of dermorphin/deltorphin (Tyr‐D‐Aaa^2^‐Phe‐Aaa^4^‐NH~2~) has been synthesized. The synthesis of the linear precursor peptides was accomplished by the solid‐phase method and ring formation was achieved via a urei

Synthesis of a novel side-chain to side-
✍ Danuta Pawlak; Ngoc Nga Chung; Peter W. Schiller; Jan Izdebski 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 110 KB 👁 2 views

A novel type of cyclic opioid peptide analogue, cyclo[N epsilon,N epsilon'-carbonyl-D-Lys2,Lys5]enkephalinamide, was prepared from a linear precursor peptide. The peptide was synthesized on the Merrified resin and also by a combination of the solid-phase technique and the classical method in solutio

Highly potent side-chain to side-chain c
✍ Danuta Pawlak; Marta Oleszczuk; Jacek Wójcik; Maria Pachulska; Nga N. Chung; Pet 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 279 KB

## Abstract Six novel cyclic enkephalin analogues have been synthesized. Cyclization of the linear peptides containing basic amino acid residues in position 2 and 5 was achieved by treatment with bis(4‐nitrophenyl)carbonate. It was found that some of the compounds exibit unusually high __µ__‐opioid

Ureido group containing cyclic dermorphi
✍ Ewa Witkowska; MichaŁ Nowakowski; Marta Oleszczuk; Katarzyna Filip; MaŁgorzata C 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 360 KB

## Abstract Six cyclic peptides related to dermorphin(1–7) have been synthesized. The synthesis of linear peptides containing diamino acid residues in positions 2 and 4 was carried out on a 4‐methylbenzhydrylamine resin, and cyclization was achieved by treatment with bis‐(4‐nitrophenyl)carbonate to