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Cyclic changes in cAMP concentration and phosphodiesterase activity in a mammalian circadian clock studied in vitro

โœ Scribed by Rebecca A. Prosser; Martha U. Gillette


Book ID
115802243
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
987 KB
Volume
568
Category
Article
ISSN
0006-8993

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Changes in camp phosphodiesterase activi
โœ Alan Dardik; Richard M. Schultz ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 553 KB

## Abstract Cyclic nucleotide phosphodiesterase (PDE) activity and cAMP amounts were measured in mouse preimplantation embryos at the 1โ€cell, 2โ€cell, 8โ€cell/ morula, and midโ€blastocyst stages. PDE activity remained constant between the 1โ€cell and 2โ€cell stages. It decreased by the 8โ€cell stage and