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Cyclic AMP phosphodiesterase activity at the external surface of intact skeletal muscles and stimulation of the enzyme by insulin

✍ Scribed by Yin-Tak Woo; J.F. Manery

Book ID
115701616
Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
970 KB
Volume
154
Category
Article
ISSN
0003-9861

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✍ Walker Wharton; Barry Goz 📂 Article 📅 1979 🏛 John Wiley and Sons 🌐 English ⚖ 681 KB

## Abstract The three xanthine derivatives, caffeine, theophylline and 3‐isobutyl‐1‐methyl‐xanthine (IBMX) produced dose‐dependent increases in cyclic AMP concentrations in HeLa cells after long term treatment. Only IBMX produced increases over the first 60 minutes, with a peak of approximately 5‐f