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Cyclic AMP and tumor promoters cause differential induction of ornithine decarboxylase and accumulation of putrescine in Chinese hamster ovary cells deficient in cyclic AMP-dependent protein kinase

✍ Scribed by Trevillyan, James M.; Byus, Craig V.


Book ID
122874594
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
897 KB
Volume
762
Category
Article
ISSN
0167-4889

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## Abstract Ornithine decarboxylase (ODC) inductions by cholera toxin and by the phorbol ester tumor promoter, TPA, were compared in wild‐type Chinese hamster ovary (CHO) cells and in mutant cells having altered cyclic AMP‐dependent protein kinase activity. The aim of these studies was to determine