Cyclecondensation of 3-amino-1,2,4-triazole with substituted methyl cinnamates

✍ Scribed by Sergey M. Desenko; Victoria V. Lipson; Oleg V. Shishkin; Sergey A. Komykhov; Valery D. Orlov; Evgeny E. Lakin; Valery P. Kuznetsov; Herbert Meier

• Publisher: Journal of Heterocyclic Chemistry
• Year: 1999
• Tongue: English
• Weight: 208 KB
• Volume: 36
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.5570360131

✦ Synopsis

Abstract

The reaction of 3‐amino‐1,2,4‐triazole (1) with substituted methyl cinnamates 2a‐h leads selectively to the formation of 7‐aryl‐6,7‐dihydro[1,2,4]triazolo[1,5‐a]pyrimidin‐5(4__H__)‐ones 3a‐h. The structure eluci dation of the products is based on ir, ^1^H and ^13^C nmr measurements and X‐ray diffraction.