Cyathiformines A–D, new chorismate-derived metabolites from the fungus clitocybe cyathiformis

✍ Scribed by Alberto Arnone; Rosanna Cardillo; Gianluca Nasini; Orso Vajna de Pava

• Book ID: 104204406
• Publisher: Elsevier Science
• Year: 1993
• Tongue: French
• Weight: 456 KB
• Volume: 49
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(01)87202-1

✦ Synopsis

Cyathiformines A-D, 1, 4a, 5 and 6a, have been isolated from the Basidiomycetous fungus Clitocybe cyathiformis. Structural determination was based on NMR studies and chemical evidence. During screening of the genus Clitocybe (Basidiomycetae) for secondary metabolites. we have reported the isolation from C. illudens, C. elegans and C. candicans of a large number of protoilludanic sesquiterpenes.2"Further investigations led to the isolation from a strain of C. cyathifonnis of an unexpected series of chorismic acid derivatives. This paper describes the isolation and characterisation of these metabolites, named cyathiformines A-D 1,4a, 5 and 6a. 4a R=H 4b R=Ac 6a R=H 6b R=Ac *Dedicated to Professor Max Viscontini on the occasion of his'80th birthday