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Cy5.5-DTPA-galactosyl-dextran: a fluorescent probe for in vivo measurement of receptor biochemistry

✍ Scribed by David R. Vera; David J. Hall; Carl K. Hoh; Pascal Gallant; Laura M. McIntosh; Robert F. Mattrey

Book ID: 116798876
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 244 KB
Volume: 32
Category: Article
ISSN: 0969-8051
DOI: 10.1016/j.nucmedbio.2005.04.003

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## Abstract 2‐(4‐Methoxyphenyl)‐__N__‐(4‐methylbenzyl)‐__N__‐(1‐methylpiperidin‐4‐yl)acetamide (AC90179, **4**), a highly potent and selective competitive 5‐HT~2A~ antagonist, was labeled by [^11^C]‐methylation of the corresponding desmethyl analogue **5** with [^11^C]methyl triflate. The precursor