Therapeutic potential of the chemokine r
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Hiroshi Tsutsumi; Tomohiro Tanaka; Nami Ohashi; Hiroyuki Masuno; Hirokazu Tamamu
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Article
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2007
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Wiley (John Wiley & Sons)
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English
β 200 KB
π 1 views
## Abstract The chemokine receptor CXCR4 possesses multiple critical functions in normal and pathologic physiology. CXCR4 is a Gβproteinβcoupled receptor that transduces signals of its endogenous ligand, the chemokine CXCL12 (stromal cellβderived factorβ1, SDFβ1). The interaction between CXCL12 and