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CXCR3 polymorphism is associated with male gender and pleuritis in patients with systemic lupus erythematosus

✍ Scribed by Im, Churl Hyun; Park, Ji Ah; Kim, Jeong Yeon; Lee, Eun Young; Lee, Eun Bong; Kim, Yeonjung; Song, Yeong Wook


Book ID
122205375
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
336 KB
Volume
75
Category
Article
ISSN
0198-8859

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Osteopontin (SPP1) is a soluble ligand with pleomorphic immunologic activities including activation of macrophage chemotaxis, promotion of Th1 responses, and activation of B1 B cells. It has been implicated in the development of murine lupus and is overexpressed in humans with systemic lupus erythem