CXCL4L1 inhibits angiogenesis and induces undirected endothelial cell migration without affecting endothelial cell proliferation and monocyte recruitment

A novel butyrolactone derivative inhibit

A novel butyrolactone derivative inhibited smooth muscle cell migration and proliferation and maintained endothelial cell functions through selectively affecting Na, K-ATPase activity and mitochondria membrane potential during in vitro angiogenesis

✍ Ning Meng; Jing Zhao; BaoXiang Zhao; Yizhe Cheng; Weiwei Wang; Yun Zhang; ShangL 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 223 KB

## Abstract We have found that 3‐benzyl‐5‐((2‐nitrophenoxy) methyl)–dihydrofuran ‐2(3H)‐one (3BDO), could effectively suppress human umbilical vascular endothelial cell (HUVEC) apoptosis induced by deprivation of fibroblast growth factor‐2 and serum. Here, our purpose was to investigate whether 3BD