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CXCL16 in HIV infection – a link between inflammation and viral replication

✍ Scribed by L. Landrø; J. K. Damås; B. Halvorsen; B. Fevang; T. Ueland; K. Otterdal; L. Heggelund; S. S. Frøland; P. Aukrust

Book ID
108713884
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
283 KB
Volume
39
Category
Article
ISSN
0014-2972

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Recent studies suggest that the pathogenesis of HIV infection and AIDS involves two distinct phases. During acute infection, massive depletion of CD4 + CCR5 + memory T cells within the mucosal-associated lymphoid tissue leads to major and potentially irreversible damage to CD4 + T-cell-mediated immu