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CXC chemokine receptor 4 signaling upon co-activation with stromal cell-derived factor-1α and ubiquitin

✍ Scribed by Tripathi, Abhishek; Davis, Jeffrey D.; Staren, Daniel M.; Volkman, Brian F.; Majetschak, Matthias


Book ID
123581822
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
906 KB
Volume
65
Category
Article
ISSN
1043-4666

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## Abstract The stromal cell‐derived factor‐1 (SDF‐1)/CXC receptor 4 (CXCR4) axis has been shown to play a role in colorectal cancer progression. In addition, the protease urokinase‐type plasminogen activator (uPA) is an important factor in tumor cell invasion and metastasis. However, the mechanism