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Cv-4151 — a potent, selective thromboxane A2synthetase inhibitor

✍ Scribed by Z. Terashita; Y. Imura; M. Tanabe; K. Kawazoe; K. Nishikawa; K. Kato; S. Terao


Book ID
119036137
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
960 KB
Volume
41
Category
Article
ISSN
0049-3848

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The effect of CV-4151, a selective inhib
✍ Tsunehiko Kuzuya; Yoshihiro Kimura; Shiro Hoshida; Kazuhisa Kodama; Nobuto Nakam 📂 Article 📅 1988 🏛 Springer US 🌐 English ⚖ 585 KB

The pharmacokinetics and pharmacologic effects of a potent, selective inhibitor of thromboxane synthetase, CV-4151 [(E)-7-phenyl-7-(3-pyridyl)-6-heptenoic acid] on prostanoid formation and platelet aggregation were studied in 42 healthy male volunteers. The drug was well tolerated. After oral admini