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Cutaneous malignant melanoma in women and the role of oral contraceptives

✍ Scribed by Gefeller; Hassan; Wille

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 276 KB
Volume: 138
Category: Article
ISSN: 0007-0963
DOI: 10.1046/j.1365-2133.1998.02037.x

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✦ Synopsis

The role of oral contraceptives (OC) in the aetiology of cutaneous malignant melanoma (CMM) has been controversially discussed over the last two decades. In an extensive literature search we identified 18 case-control studies, published between 1977 and 1996, offering information on this relationship. Using a meta-analytical approach we combined the study-specific risk estimates and derived a summary odds ratio of 0.95 (95% confidence interval: 0.87-1.04). Based on the data of 3796 cases and 9442 controls, we thus found no evidence for an aetiological role of OC use in the development of CMM.

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