Cutaneous allergy (urticaria) to insulin preparations

✍ Scribed by Brooks, AP ;Roseveare, CD

• Book ID: 104514348
• Publisher: John Wiley and Sons
• Year: 1994
• Tongue: English
• Weight: 408 KB
• Volume: 11
• Category: Article
• ISSN: 1357-8170
• DOI: 10.1002/pdi.1960110606

✦ Synopsis

Abstract

Five patients are described who experienced generalised cutaneous reactions, urticarla and itching, after Injecting varlous modern human insulln preparations. This allergy was not due to the Insulin, but to some of the non‐Insulin components of Insulin solutions. Prick‐skin testing Identified the specific allergen in each patient; In three cases, protamine. Change to another human insulin preparation without the allergen in its constltuents resolved the symptoms in each patient.