Customized solid supports for small-molecule synthesis: effects of crosslinking structure and degree

✍ Scribed by Michael D Price; Jennifer L Radosevich; Mark J Kurth; Neil E Schore

• Book ID: 104425229
• Publisher: Elsevier Science
• Year: 2003
• Tongue: English
• Weight: 116 KB
• Volume: 55
• Category: Article
• ISSN: 1381-5148
• DOI: 10.1016/s1381-5148(02)00222-5

✦ Synopsis

Divinylbenzene (DVB) and diethylene glycol bis(4-vinylbenzyl) ether (DEG) were used as crosslinkers in the preparation of four resins of mixed micro-and macroporous character and differing polarity to examine the effects of crosslinker structure and macroporosity. The Suzuki coupling process was used as the probe reaction for this purpose. Results with 2% DVB, 2% DEG, 5% DEG and 15% DEG indicate that the DEG-crosslinked resins are somewhat better suited for this process, although the degree of crosslinking appears to have only minimal effect of degree of conversion to product.