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Curtailing Overexpression of E2F3 in Breast Cancer Using siRNA (E2F3)-Based Gene Silencing

โœ Scribed by Vimala, Karuppaiya; Sundarraj, Shenbagamoorthy; Sujitha, Mohanan V.; Kannan, Soundarapandian

Book ID
118416516
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
881 KB
Volume
43
Category
Article
ISSN
0188-4409

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## Abstract E2F3a is a transcription factor that has been shown to be overexpressed in liver cancer tissues. To characterize the function of E2F3a in hepatocellular carcinoma (HCC), effects of ectopic overexpression of E2F3a on cell cycle, apoptosis, and gene expression of HepG2 cells were studied.