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โœฆ   LIBER   โœฆ

[Current Topics in Microbiology and Immunology] Interleukin-10 in Health and Disease Volume 380 || The Role of microRNAs in the Control and Mechanism of Action of IL-10

โœ Scribed by Fillatreau, Simon; O'Garra, Anne

Book ID
126162681
Publisher
Springer Berlin Heidelberg
Year
2014
Tongue
German
Weight
370 KB
Edition
2014
Category
Article
ISBN
366243492X

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โœฆ Synopsis

This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 recognition by its receptor functions. The roles of T and B cells as relevant sources of IL-10 are also discussed, with an emphasis on the clinical opportunities offered by IL-10-producing Tr1 cells for the suppression of unwanted immunity. Finally, the functions of other cytokines of the IL-10 family are presented. Collectively, these articles provide a comprehensive overview of our current knowledge on one of the most important anti-inflammatory cytokines known to date.

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