[Current Topics in Microbiology and Immunology] Cell Entry by Non-Enveloped Viruses Volume 343 || From Touchdown to Transcription: The Reovirus Cell Entry Pathway

✍ Scribed by Johnson, John E.

• Book ID: 120339043
• Publisher: Springer Berlin Heidelberg
• Year: 2010
• Tongue: German
• Weight: 604 KB
• Edition: 2010
• Category: Article
• ISBN: 3642133320
• DOI: 10.1007/82_2010_32

✦ Synopsis

The means by which non-enveloped viruses penetrate cellular membranes during cell entry remain poorly defined. Recent findings indicate several members of this group share a common mechanism of membrane penetration in which the virus particle undergoes programmed conformational changes, leading to capsid disassembly and release of small membrane-interacting peptides. A complete understanding of host cell entry by this minimal system will help elucidate the mechanisms of non-enveloped virus membrane penetration in general