CURRENT THERAPY FOR LANGERHANS CELL HISTIOCYTOSIS
β Scribed by Broadbent, Valerie; Gadner, Helmut
- Book ID
- 123359075
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 588 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0889-8588
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## Abstract Optimal treatment for Langerhans Cell Histiocytosis (LCH) has not yet been established. Preliminary reports suggest some effect of cyclosporine (CSA), both alone or in combination with steroids and/or vinblastine, in untreated cases. Twelve children (6 females and 6 males, age at diagno
Background. Treatment of multisystem Langerhans cell histiocytosis (LCH) remains difficult. Various regimens of single and multiagent chemotherapy have been used, but a significant proportion of patients fail to respond to treatment. Procedure. We have evaluated the use of cyclosporine A (CSA) in a