𝔖 Bobbio Scriptorium
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Current Status of Platinum-Based Antitumor Drugs

✍ Scribed by Wong, Ernest; Giandomenico, Christen M.


Book ID
111931528
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
326 KB
Volume
99
Category
Article
ISSN
0009-2665

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The discovery in the 1990s of several trans-Pt complexes with in vitro and in vivo activity against tumor cells sensitive and/or resistant to cisplatin has forced the re-evaluation of the structure-activity relationships for platinum antitumor drugs. Because the determinant factors of cytotoxic acti