Current status of gene therapy trials for Parkinson's disease
β Scribed by Massimo Fiandaca; John Forsayeth; Krystof Bankiewicz
- Book ID
- 116459202
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 664 KB
- Volume
- 209
- Category
- Article
- ISSN
- 0014-4886
No coin nor oath required. For personal study only.
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Symptomatic medical therapies for Parkinson's disease (PD) have been disease modifying and have led to improvement in daily function, quality of life, and survival. For 40 years, these therapies have been primarily dopaminergic, and currently include the dopamine (DA) precursor levodopa (LD), DA ago
## Abstract The once fantastic theoretical concept that patients with Parkinson's disease (PD) would receive gene therapy in an attempt to alleviate their symptoms and potentially modify the course of their disease has become a reality. On the basis of positive preclinical data, four different gene