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Current status of gene therapy for rheumatoid arthritis

✍ Scribed by Daniel F. Gaddy; Paul D. Robbins


Book ID
107554029
Publisher
Springer
Year
2008
Tongue
English
Weight
324 KB
Volume
10
Category
Article
ISSN
1523-3774

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## Abstract Rheumatoid arthritis (RA) is a severe autoimmune systemic disease. Chronic synovial inflammation results in destruction of the joints. No conventional treatment is efficient in RA. Gene therapy of RA targets mainly the players of inflammation or articular destruction: TNF‐α or IL‐1 bloc

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## Background and objective: The only early surgical therapy of rheumatoid arthritis is synovectomy. but even an arthroscopic synovectomy is restricted to more or less big joints. it has been shown recently that for smaller joints a laser synovectomy is possible but more time-consuming than with me