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Current Protocols in Human Genetics || Evaluation of the Mitochondrial Respiratory Chain and Oxidative Phosphorylation System Using Blue Native Gel Electrophoresis

โœ Scribed by Haines, Jonathan L.; Korf, Bruce R.; Morton, Cynthia C.; Seidman, Christine E.; Seidman, J.G.; Smith, Douglas R.


Book ID
119991525
Publisher
Wiley (John Wiley & Sons)
Year
2009
Tongue
English
Weight
128 KB
Volume
63
Category
Article
ISBN-13
9780471142904
ISSN
1934-8266

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Mitochondrial dysfunction and degeneration are associated with many neurodegenerative disorders. A dysfunctional mitochondrial electron transport chain (ETC) impairs ATP production and accelerates the generation of free radicals. To evaluate mitochondrial function, reliable methods are needed. Conve