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Current Protocols in Cell Biology || Inducible Gene Expression Using an Autoregulatory, Tetracycline-Controlled System

โœ Scribed by Bonifacino, Juan S.; Dasso, Mary; Harford, Joe B.; Lippincott-Schwartz, Jennifer; Yamada, Kenneth M.


Book ID
120028957
Publisher
Wiley (John Wiley & Sons)
Year
2005
Tongue
English
Weight
143 KB
Volume
27
Category
Article
ISBN-13
9780471143031
ISSN
1934-2500

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Background Nonviral ex vivo local gene therapy systems consisting of regulated gene expression vectors and cellular delivery platforms represent a novel strategy for tissue repair and regeneration. We introduced a hypoxiaregulated plasmid-based system into mouse neural stem cells (NSCs) as an effici