## Background: The clinical course of adult granulosa cell tumor of the ovary is characterized by indolent growth tending toward late recurrence. a variety of clinical and pathologic parameters have previously been evaluated for prognostication with inconclusive results. ## Methods: The clinical
Current knowledge in the renewal capability of germ cells in the adult ovary
โ Scribed by Ozgur Oktem; Kutluk Oktay
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 79 KB
- Volume
- 87
- Category
- Article
- ISSN
- 1542-975X
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We report the cytogenetic findings in a case of mixed germ cell-sex cord-stromal tumor of the ovary in a 5-month-old girl. Monosomy 22 was observed as the sole karyotypic abnormality. This result was confirmed by comparative genomic hybridization, which revealed no additional chromosomal imbalances.
The germ cell lineage in mice becomes lineage-restricted about 7.2 days post coitum. Its progenitors have migrated from the proximal region of the epiblast. Cells from the distal region of the epiblast will also give rise to germ cells, if they are transplanted to the proximal region at the appropri