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Current assessment of polo-like kinases as anti-tumor drug targets

✍ Scribed by Craig, Sandra N; Wyatt, Michael D; McInnes, Campbell

Book ID
121867132
Publisher
Informa plc
Year
2014
Tongue
English
Weight
890 KB
Volume
9
Category
Article
ISSN
1746-0441

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## Abstract Down‐modulation of target molecules in tumor cells by small interfering (si) RNAs is a promising anti‐cancer strategy. A major challenge of this approach is the loss of silencing activity of the siRNAs __in vivo__. Our study aimed at investigating the influence of the serum compartment