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Current and future adjuvant immunotherapies for melanoma: Blockade of cytotoxic T-lymphocyte antigen-4 as a novel approach

✍ Scribed by Sanjiv S. Agarwala; Steven J. O’Day


Book ID
116395512
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
307 KB
Volume
37
Category
Article
ISSN
0305-7372

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## Abstract Cancer immunotherapy centers on modulating the host's tumor‐directed immune response. One promising approach involves augmentation of cell‐mediated immunity by interrupting T‐cell pathways responsible for immune down‐regulation or tolerance. The discovery of cytotoxic T‐lymphocyte antig