Curing CNS autoimmune disease with myelin-reactive Foxp3+ Treg

Decreased CNS inflammation and absence o

Decreased CNS inflammation and absence of clinical exacerbation of disease after six months oral administration of bovine myelin in diseased SJL/J mice with chronic relapsing experimental autoimmune encephalomyelitis

✍ A.M. Al-Sabbagh; E.P. Goad; H.L. Weiner; P.A. Nelson 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 588 KB

Murine chronic relapsing experimental autoimmune encephalomyelitis (CR-EAE) is a model of inflammatory demyelinating disease of the central nervous system (CNS) with similarity to multiple sclerosis (MS) in humans. Mice with confirmed neurologic deficits from CR-EAE were treated by oral administrati